Human TM4SF1 VLP Protein
Catalog No: TM4SF1-HP001
- Species
- Human
- Expression System
- HEK293
Product overview
Human TM4SF1 VLP Protein is a full-length multi-pass membrane protein presented in a VLP format for antibody discovery, binding assays and method development. Recombinant Human TM4SF1 VLP is expressed from HEK293. It contains Met1-Cys202 (It may have cross reaction with anti-His antibody) (accession: P30408).
Product Details
- Molecular Aliases
- M3S1; TAAL6; H-L6; L6
- Protein Length
- Met1-Cys202
- Expression System
- HEK293
- Theoretical Molecular Weight
- The target protein has a predicted MW of 21.64 kDa.
- Purity
- > 95% as determined by HPLC
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
- State
- Liquid
- Storage Conditions
- Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.
Background
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
References
- Yang JC, Zhang Y, He SJ, Li MM, Cai XL, Wang H, Xu LM, Cao J. TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. Sci Rep. 2017 Apr 3;7:45895. doi: 10.1038/srep45895. PMID: 28368050; PMCID: PMC5377454.
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