PROVETOP

Human SSTR2 VLP Protein

Catalog No: SSTR2-HP001

Species
Human
Expression System
HEK293

Product overview

Human SSTR2 VLP Protein is a full-length multi-pass membrane protein presented in a VLP format for antibody discovery, binding assays and method development. Recombinant Human SSTR2 VLP is expressed from HEK293. It contains Met1-Ile369 (It may have cross reaction with anti-His antibody) (accession: P30874-1).

Product Details

Molecular Aliases
SS-2-R; SS2-R; SS2R; SRIF-1; SRIF1; SRIF 1; Smstr2; SST2; SSTR2
Protein Length
Met1-Ile369
Expression System
HEK293
Theoretical Molecular Weight
The target protein has a predicted MW of 42.7 kDa.
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1 EU per μg by the LAL method.
Buffer / Formulation
Supplied as 0.22μm filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
State
Liquid
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.

Background

Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma.

References

  1. Wu W, Zhou Y, Wang Y, Liu L, Lou J, Deng Y, Zhao P, Shao A. Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma. Front Oncol. 2020 Sep 3;10:1633. doi: 10.3389/fonc.2020.01633. PMID: 33014821; PMCID: PMC7494964.

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