Biotinylated Rat uPAR/PLAUR Protein
Catalog No: PLAUR-RB001
- Species
- Rat
- Expression System
- HEK293
- Tag
- His, Avi
Product overview
Recombinant Biotinylated Rat uPAR/PLAUR Protein is expressed in HEK293 cells with a His tag and Avi tag at the C-terminus. It contains amino acid residues Leu25-Gly299 (UniProt accession: P49616-1).
Product Details
- Molecular Aliases
- U-PAR; uPAR; CD87; PLAUR; MO3; UPAR
- Protein Length
- Leu25-Gly299
- Expression System
- HEK293
- Theoretical Molecular Weight
- The protein has a predicted MW of 33.05 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
- Purity
- > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
- State
- Liquid
- Storage Conditions
- Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Data Display
Biotinylated Rat uPAR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Rat uPAR is greater than 95% as determined by SEC-HPLC.
Background
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen. Regulation of the activity of u-PA is also mediated by u-PAR.
References
- Blasi F. The urokinase receptor and cell migration. Semin Thromb Hemost. 1996;22(6):513-6. doi: 10.1055/s-2007-999053. PMID: 9122717.
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