Biotinylated Human Latent TGF beta 3/TGFB3 Protein (Primary Amine Labeling)
Catalog No: TGFB3-HB002
- Species
- Human
- Expression System
- HEK293
- Tag
- His
Product overview
Recombinant Biotinylated Human Latent TGF beta 3/TGFB3 Protein (Primary Amine Labeling) is expressed in HEK293 cells with a His tag at the N-terminus. It contains amino acid residues Leu24-Ser412 (UniProt accession: P10600-1).
Product Details
- Molecular Aliases
- TGFB3; ARVD; TGF-beta3; TGF-β; TGFβ3; TGFβ; TGF-beta 3;TGF-b; TGF-beta; TGF beta 3; TGFb; TGF beta
- Protein Length
- Leu24-Ser412
- Expression System
- HEK293
- Theoretical Molecular Weight
- The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
- Purity
- > 95% as determined by Bis-Tris PAGE
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
- State
- Liquid
- Storage Conditions
- Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Data Display
Biotinylated Human Latent TGF beta 3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Background
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos.
References
- Okamura T, Morita K, Iwasaki Y, Inoue M, Komai T, Fujio K, Yamamoto K. Role of TGF-β3 in the regulation of immune responses. Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 92):S63-9. Epub 2015 Oct 12. PMID: 26457612.
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