Mouse RETN Protein
Catalog No: RETN-MF001
- Species
- Mouse
- Expression System
- HEK293
- Tag
- an hFc (IgG1)
Product overview
Recombinant Mouse RETN Protein is expressed in HEK293 cells with an hFc (IgG1) tag at the N-terminus. It contains amino acid residues Ser21-Ser114 (UniProt accession: Q99P87).
Product Details
- Molecular Aliases
- Resistin; ADSF; FIZZ3; HXCP1; RETN; RETN1; XCP1; ADSFMGC126609; FIZZ3MGC126603; RSTNXCP1
- Protein Length
- Ser21-Ser114
- Expression System
- HEK293
- Theoretical Molecular Weight
- The protein has a predicted MW of 37.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
- Purity
- > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC
- Endotoxin
- Less than 0.1 EU per μg by the LAL method.
- Buffer / Formulation
- Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- State
- Lyophilized
- Storage Conditions
- -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Reconstitution Advice
- Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
Data Display
Mouse RETN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse RETN is greater than 90% as determined by SEC-HPLC.
Background
Resistin (RETN) is a hormone secreted by adipocytes, which plays an important role in glucose and lipid metabolism. The RETN gene is expressed in goat various analyzed tissues, and the results showed that the expression of RETN gene in lung tissue was higher than that in other analyzed tissues of goat (p <.01). Moreover, the expression level of RETN gene in the goat's intramuscular preadipocytes decreased first and then increased, and reached the highest on the fifth day, which was significantly higher than that of undifferentiated intramuscular preadipocytes.
References
- Zhang Y, Wang Y, Xu Q, Zhu J, Lin Y. Molecular and expression characteristics of resistin (RETN) and its effects on the differentiation of intramuscular preadipocyte in goat. Anim Biotechnol. 2021 Feb;32(1):113-120. doi: 10.1080/10495398.2019.1664564. Epub 2019 Sep 13. PMID: 31516062.
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