Cynomolgus CXCL10 Protein
Catalog No: CXCL10-CP001
- Species
- Cynomolgus
- Expression System
- E.coli
- Tag
- His
Product overview
Recombinant Cynomolgus CXCL10 Protein is expressed in E. coli with a His tag at the N-terminus. It contains amino acid residues Thr27-Lys91 (accession: XP_005555067.1).
Product Details
- Molecular Aliases
- C-X-C motif chemokine 10; IP-10; CXCL10(1-73); CXCL10; INP10; SCYB10; C7; crg-2; gIP-10; IFI10;; IP10; crg2; gIP10
- Protein Length
- Thr27-Lys91
- Expression System
- E.coli
- Theoretical Molecular Weight
- The protein has a predicted MW of 8.36 kDa. The protein migrates to 12-14 kDa based on Bis-Tris PAGE result.
- Purity
- > 95% as determined by Bis-Tris PAGE
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- State
- Lyophilized
- Storage Conditions
- -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Reconstitution Advice
- Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
Data Display
Cynomolgus CXCL10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Background
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothelial and vascular smooth muscle cells. CXCL10 is secreted by leukocytes and tissue cells and functions as a chemoattractant, mainly for lymphocytes.
References
- van den Borne P, Quax PH, Hoefer IE, Pasterkamp G. The multifaceted functions of CXCL10 in cardiovascular disease. Biomed Res Int. 2014;2014:893106. doi: 10.1155/2014/893106. Epub 2014 Apr 23. PMID: 24868552; PMCID: PMC4017714.
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