Human TSHR VLP Protein
Catalog No: TSHR-HP001
- Species
- Human
- Expression System
- HEK293
Product overview
Human TSHR VLP Protein is a full-length multi-pass membrane protein presented in a VLP format for antibody discovery, binding assays and method development. Recombinant Human TSHR VLP is expressed from HEK293. It contains Met1-Leu764 (It may have cross reaction with anti-His antibody) (accession: P16473).
Product Details
- Molecular Aliases
- TSH-R; LGR3; TSH R
- Protein Length
- Met1-Leu764
- Expression System
- HEK293
- Theoretical Molecular Weight
- The target protein has a predicted MW of 87.81 kDa.
- Purity
- > 95% as determined by HPLC
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Supplied as 0.22μm filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
- State
- Liquid
- Storage Conditions
- Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.
Background
Thyroid stimulating hormone receptor (TSHR) is a receptor for thyrostimulin and thyroid stimulating hormone (TSH, also called thyrotropin). TSHR is a cell surface glycoprotein receptor and belongs to the leucine-rich repeat (LGR) subfamily of G-protein-coupled receptors (GPCRs).
References
- Chu YD, Yeh CT. The Molecular Function and Clinical Role of Thyroid Stimulating Hormone Receptor in Cancer Cells. Cells. 2020 Jul 20;9(7):1730. doi: 10.3390/cells9071730. PMID: 32698392; PMCID: PMC7407617.
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