Human LGR-4 Nanodisc Protein
Catalog No: LGR4-HP001
- Species
- Human
- Expression System
- HEK293
- Tag
- His
Product overview
Human LGR-4 Nanodisc Protein is a full-length multi-pass membrane protein presented in a Nanodisc format for antibody discovery, binding assays and method development. Recombinant Human LGR-4 Nanodisc is expressed from HEK293 with His tag at the C-terminus. It contains Met1-Asp951 (accession: Q9BXB1-1).
Product Details
- Molecular Aliases
- LGR4; GPR48
- Protein Length
- Met1-Asp951
- Expression System
- HEK293
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
- State
- Liquid
- Storage Conditions
- Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.
Background
Leucine-rich repeat-containing G protein-coupled receptor (LGR)-4 is a G protein-coupled receptor (GPCR) with a seven-transmembrane domain structure. LGRs are evolutionally and structurally phylogenetic, classified into three subgroups and are members of the so-called orphan receptors.
References
- Kato S, Matsubara M, Matsuo T, Mohri Y, Kazama I, Hatano R, Umezawa A, Nishimori K. Leucine-rich repeat-containing G protein-coupled receptor-4 (LGR4, Gpr48) is essential for renal development in mice. Nephron Exp Nephrol. 2006;104(2):e63-75. doi: 10.1159/000093999. Epub 2006 Jun 19. PMID: 16785743.
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