Human APLNR VLP Protein
Catalog No: APLNR-HP001
- Species
- HEK293
- Expression System
- Met1-Asp380
Product overview
Recombinant Human APLNR VLP protein is expressed in HEK293 cells and contains Met1-Asp380 (UniProt accession: P35414). The full-length receptor is displayed in a virus-like particle format for antibody-binding, immunization and assay-development research.
Product Details
- Molecular Aliases
- Apelin receptor; AGTRL1; APJ; HG11; APJR; AR
- Protein Length
- Met1-Asp380
- Expression System
- Met1-Asp380
- Theoretical Molecular Weight
- 46.7 kDa
- Purity
- >95% (HPLC)
- Endotoxin
- <1 EU/μg (LAL assay)
- Buffer / Formulation
- PBS with 200 mM L-arginine, pH 7.4.
- Storage Conditions
- Store at -80°C for up to 12 months. Minimize freeze-thaw cycles.
Background
The apelin receptor (APJ) is a class A G protein-coupled receptor involved in the regulation of cardiovascular and central nervous system functions. APJ signaling has been studied in hypertension, atherosclerosis and cerebral stroke, making the receptor a research target in cardiovascular and neurological disease biology.
References
- Hu S, Wang D, Liu W, Wang Y, Chen J, Cai X. Apelin receptor dimer: Classification, future prospects, and pathophysiological perspectives. Biochim Biophys Acta Mol Basis Dis. 2024 Aug;1870(6):167257. doi: 10.1016/j.bbadis.2024.167257. PMID: 38795836.
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