Mouse CD164 Protein
Catalog No: CD164-MF001
- Species
- Mouse
- Expression System
- HEK293
- Tag
- an hFc (IgG1)
Product overview
Recombinant Mouse CD164 Protein is expressed in HEK293 cells with an hFc (IgG1) tag at the C-terminus. It contains amino acid residues Gln24-Asp162 (UniProt accession: Q9R0L9).
Product Details
- Molecular Aliases
- MUC-24; Endolyn; MGC-24; Cd164; CD164; MGC-24v; sialomucin;MUC24; MGC24; MGC24v
- Protein Length
- Gln24-Asp162
- Expression System
- HEK293
- Theoretical Molecular Weight
- The protein has a predicted MW of 41.4 kDa. Due to glycosylation, the protein migrates to 70-115 kDa based on Bis-Tris PAGE result.
- Purity
- > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
- Endotoxin
- Less than 1 EU per μg by the LAL method.
- Buffer / Formulation
- Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
- State
- Lyophilized
- Storage Conditions
- -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Reconstitution Advice
- Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
Data Display
Mouse CD164 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CD164 is greater than 95% as determined by SEC-HPLC.
Background
CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients.CD164 was associated with the poor clinical outcomes of BC patients. Silencing of CD164 could inhibit the progression of tumors in vivo and in vitro, which may become an effective target in the treatment of bladder cancer.
References
- Zhang XG, Zhang T, Li CY, Zhang MH, Chen FM. CD164 promotes tumor progression and predicts the poor prognosis of bladder cancer. Cancer Med. 2018 Aug;7(8):3763-3772. doi: 10.1002/cam4.1607. Epub 2018 Jul
- PMID: 30022623; PMCID: PMC6089154. Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.
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