PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein
Catalog No: MAGEA1-HP004
- Species
- Human
- Expression System
- HEK293
- Tag
- His, Avi
Product overview
Recombinant PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide (accession: A0A140T913(HLA-A*02:01) & P61769(B2M) &KVLEYVIKV).
Product Details
- Molecular Aliases
- MAGE-A1; MAGE A1; CT1.1; MAGE-1 antigen; MAGE-1; MZ2-E; MAGE1; MAGE1A
- Protein Length
- Gly25-Thr305
- Expression System
- HEK293
- Buffer / Formulation
- Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4).
- State
- Liquid
- Storage Conditions
- Valid for 6 months from date of receipt when stored at -80°C; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Background
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
References
- Wang D, Wang J, Ding N, Li Y, Yang Y, Fang X, Zhao H. MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation. Biochem Biophys Res Commun. 2016 May 13;473(4):959-965. doi: 10.1016/j.bbrc.2016.03.161. Epub 2016 Apr 1. PMID: 27045082.
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