PE-Labeled Human PD-1/PDCD1 Protein
Catalog No: PD1-HP003
- Species
- Human
- Expression System
- HEK293
- Tag
- His
Product overview
Recombinant PE-Labeled Human PD-1/PDCD1 Protein is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Leu25-Gln167 (UniProt accession: Q15116).
Product Details
- Molecular Aliases
- PDCD1; PD1; CD279; SLEB2; PD-1
- Protein Length
- Leu25-Gln167
- Expression System
- HEK293
- Theoretical Molecular Weight
- The protein has a predicted MW of 17 kDa.
- Buffer / Formulation
- Supplied as 0.22μm filtered solution in PBS (pH 7.4).
- State
- Liquid
- Storage Conditions
- Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Background
Programmed cell death protein 1, also known as PD-1 and CD279, is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
References
- Blank C, Mackensen A. Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion[J]. Cancer Immunology Immunotherapy, 2007, 56(5):739-745.
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