.bio-topic-page{--bio-navy:#092742;--bio-deep:#061d33;--bio-teal:#159b9a;--bio-teal-dark:#0d7878;--bio-orange:#ef7d3c;--bio-text:#243746;--bio-muted:#5b6b78;--bio-light:#f3f6f8;--bio-line:#d9e2e8;color:var(--bio-text);font:16px/1.7 Inter,Arial,Helvetica,sans-serif}
.bio-topic-page *{box-sizing:border-box}.bio-topic-page h1,.bio-topic-page h2,.bio-topic-page h3{font-family:Inter,Arial,Helvetica,sans-serif}.bio-topic-page img{display:block;max-width:100%}.bio-topic-page a{text-decoration:none}.bio-topic-page h2{margin:0 0 28px;color:var(--bio-navy);font-size:32px;line-height:1.22;letter-spacing:-.02em}.bio-topic-page h3{color:var(--bio-navy)}
.bio-topic-hero{position:relative;height:630px;overflow:hidden;background:var(--bio-deep);color:#fff}.bio-topic-hero-media{position:absolute;inset:0;width:100%;height:100%;object-fit:cover;object-position:center}.bio-topic-hero::after{content:"";position:absolute;z-index:1;inset:0;background:linear-gradient(90deg,rgba(6,29,51,.98) 0%,rgba(6,29,51,.9) 39%,rgba(6,29,51,.42) 65%,rgba(6,29,51,.06) 100%)}.bio-topic-hero-inner{position:relative;z-index:2;height:100%;display:flex;align-items:center}.bio-topic-hero-copy{max-width:620px}.bio-topic-hero h1{max-width:650px;margin:0 0 18px;color:#fff;font-size:46px;line-height:1.08;letter-spacing:-.025em;text-shadow:0 2px 18px rgba(0,0,0,.18)}.bio-topic-hero p{max-width:560px;margin:0 0 28px;color:#e0ebf2;font-size:18px;line-height:1.65}.bio-topic-hero-button{min-height:44px;padding:0 22px;display:inline-flex;align-items:center;justify-content:center;border:1px solid #fff;border-radius:24px;background:#fff;color:var(--bio-navy);font-size:14px;font-weight:700}.bio-topic-hero-button:hover{background:#eef8f7;color:var(--bio-teal-dark)}.bio-topic-hero-button:focus-visible{outline:3px solid #82d2d0;outline-offset:3px}
.bio-topic-nav{position:sticky;top:78px;z-index:15;border-bottom:1px solid var(--bio-line);background:rgba(255,255,255,.97);backdrop-filter:blur(10px)}.admin-bar .bio-topic-nav{top:110px}.bio-topic-nav .container{min-height:64px;display:flex;align-items:center;gap:40px;overflow-x:auto}.bio-topic-nav a{min-height:64px;display:flex;align-items:center;border-bottom:3px solid transparent;color:var(--bio-navy);font-size:15px;font-weight:700;white-space:nowrap}.bio-topic-nav a:hover,.bio-topic-nav a:focus-visible,.bio-topic-nav a.is-active{border-bottom-color:var(--bio-teal);color:var(--bio-teal-dark)}.bio-topic-nav .bio-topic-quick{min-height:42px;margin-left:auto;padding:0 20px;border:1px solid var(--bio-teal);border-radius:22px}
.bio-topic-overview{padding:64px 0 72px;background:#fff}.bio-topic-overview-copy{width:100%;margin:0;color:var(--bio-text);font-size:16px;line-height:1.7}.bio-topic-highlights{max-width:1040px;margin:44px auto 0;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:48px}.bio-topic-highlights article{text-align:center}.bio-topic-highlight-icon{position:relative;width:72px;height:72px;margin:0 auto 16px;display:grid;place-items:center;border-radius:50%;background:#eef7f7;box-shadow:0 8px 20px rgba(9,39,66,.06)}.bio-topic-highlight-icon::before,.bio-topic-highlight-icon::after{content:"";position:absolute;border-radius:50%}.bio-topic-highlight-icon::before{right:5px;top:8px;width:17px;height:17px;background:var(--bio-teal)}.bio-topic-highlight-icon::after{left:7px;bottom:8px;width:11px;height:11px;border:3px solid #82d2d0}.bio-topic-highlight-icon svg{position:relative;z-index:2;width:32px;height:32px;stroke:var(--bio-navy)}.bio-topic-highlights article:nth-child(2) .bio-topic-highlight-icon::before{background:var(--bio-orange)}.bio-topic-highlights article:nth-child(2) svg{stroke:var(--bio-teal-dark)}.bio-topic-highlights article:nth-child(3) .bio-topic-highlight-icon::after{border-color:var(--bio-orange)}.bio-topic-highlights h3{margin:0 0 5px;font-size:16px;line-height:1.4}.bio-topic-highlights p{max-width:250px;margin:0 auto;color:var(--bio-muted);font-size:14px;line-height:1.55}
.bio-topic-assay{padding:72px 0 80px;background:var(--bio-light)}.bio-topic-section-head{margin-bottom:32px}.bio-topic-section-head>span{display:block;width:48px;height:6px;margin-bottom:16px;background:var(--bio-teal)}.bio-topic-section-head h2{margin-bottom:8px}.bio-topic-section-head p{max-width:900px;margin:0;color:var(--bio-muted);font-size:16px}.bio-topic-assay-layout{display:grid;grid-template-columns:minmax(0,3fr) minmax(260px,1fr);gap:40px}.bio-topic-route figure{margin:0 0 8px}.bio-topic-route figure img{width:100%;height:auto}.bio-topic-route-copy{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:24px;text-align:center}.bio-topic-route-copy h3{margin:0 0 8px;font-size:20px}.bio-topic-route-copy p{min-height:52px;margin:0 auto 18px;color:var(--bio-muted);font-size:14px;line-height:1.55}.bio-topic-route-copy strong{min-width:190px;min-height:36px;padding:7px 12px;display:inline-flex;align-items:center;justify-content:center;border-radius:999px;background:#eaf6f5;color:var(--bio-teal-dark);font-size:13px}.bio-topic-route-copy p:last-child{min-height:0;margin-top:16px}.bio-topic-labeling{padding-left:36px;border-left:1px solid var(--bio-line)}.bio-topic-labeling>h3{margin:0 0 2px;font-size:20px}.bio-topic-labeling>p{margin:0 0 26px;color:var(--bio-muted);font-size:14px}.bio-topic-labeling-method{position:relative;padding:0 0 28px 52px}.bio-topic-labeling-method+.bio-topic-labeling-method{padding-top:18px}.bio-topic-method-dot{position:absolute;left:0;top:2px;width:36px;height:36px;border-radius:50%;background:var(--bio-teal)}.bio-topic-labeling-method--amine .bio-topic-method-dot{top:20px;background:var(--bio-orange)}.bio-topic-labeling-method h3{margin:0 0 16px;font-size:20px}.bio-topic-labeling-method ul{display:grid;gap:12px;margin:0;padding:0;list-style:none}.bio-topic-labeling-method li{display:grid;grid-template-columns:32px 1fr;gap:10px;align-items:start;color:var(--bio-muted);font-size:14px;line-height:1.5}.bio-topic-labeling-method li span{width:32px;height:32px;display:grid;place-items:center;border-radius:50%;background:#e3f4f3;color:var(--bio-teal-dark);font-size:18px;font-weight:800}.bio-topic-labeling-method--amine li span{background:#fff0e7;color:var(--bio-orange)}
.bio-topic-products{padding:72px 0 80px;background:#fff}.bio-topic-groups{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin-bottom:24px}.bio-topic-groups button{width:100%;min-height:76px;padding:15px 18px;border:1px solid var(--bio-line);border-radius:10px;background:#fff;color:var(--bio-navy);text-align:left;cursor:pointer;box-shadow:0 4px 15px rgba(9,39,66,.04)}.bio-topic-groups button strong,.bio-topic-groups button span{display:block}.bio-topic-groups button strong{font-size:15px}.bio-topic-groups button span{margin-top:2px;color:var(--bio-muted);font-size:13px}.bio-topic-groups button.is-active{border-color:var(--bio-teal);background:#eaf6f5;box-shadow:inset 0 -3px 0 var(--bio-teal)}.bio-topic-groups button:focus-visible{outline:3px solid var(--bio-teal);outline-offset:3px}.bio-topic-filters{display:grid;grid-template-columns:minmax(280px,1.45fr) minmax(170px,1fr) minmax(170px,1fr) 150px;gap:12px;padding:16px;margin-bottom:24px;border-radius:10px;background:#edf2f5}.bio-topic-filters label{position:relative}.bio-topic-filters input,.bio-topic-filters select{width:100%;height:48px;padding:0 16px;border:1px solid #bdcbd5;border-radius:5px;background:#fff;color:var(--bio-text);font-size:15px}.bio-topic-filters input:focus-visible,.bio-topic-filters select:focus-visible{outline:3px solid var(--bio-teal);outline-offset:2px}.bio-topic-search input{padding-right:54px}.bio-topic-search>span:last-child{position:absolute;right:0;top:0;width:54px;height:48px;display:grid;place-items:center;border-radius:0 5px 5px 0;background:var(--bio-navy);color:#fff}.bio-topic-search svg{width:20px;height:20px}.bio-topic-count{height:48px;display:flex;align-items:center;justify-content:center;border-radius:5px;background:#fff;color:var(--bio-navy);font-size:14px}.bio-topic-count strong{margin-right:5px;color:var(--bio-teal-dark);font-size:18px}.bio-topic-product-list{display:grid;gap:16px}.bio-topic-product{min-height:190px;display:grid;grid-template-columns:minmax(0,1fr) 280px;overflow:hidden;border:1px solid var(--bio-line);border-radius:10px;background:#fff;box-shadow:0 8px 24px rgba(9,39,66,.055)}.bio-topic-product[hidden]{display:none}.bio-topic-product-copy{padding:30px 34px}.bio-topic-product-copy>span{display:block;margin-bottom:7px;color:var(--bio-teal-dark);font-size:13px;font-weight:700}.bio-topic-product h3{margin:0 0 16px;font-size:20px}.bio-topic-product h3 a:hover{color:var(--bio-teal-dark)}.bio-topic-product dl{display:flex;flex-wrap:wrap;gap:8px 28px;margin:0;color:var(--bio-muted);font-size:14px}.bio-topic-product dl div{display:flex;gap:8px}.bio-topic-product dt{color:var(--bio-text);font-weight:700}.bio-topic-product dd{margin:0}.bio-topic-product-copy p{margin:18px 0 0;color:var(--bio-muted);font-size:13px}.bio-topic-product-data{padding:18px;display:grid;place-items:center;border-left:1px solid var(--bio-line);background:#f7fafb}.bio-topic-product-data img{width:100%;height:150px;object-fit:contain}.bio-topic-product-data:focus-visible{outline:3px solid var(--bio-teal);outline-offset:-4px}.bio-topic-empty{margin:0;padding:34px;text-align:center;color:var(--bio-muted)}.bio-topic-empty[hidden]{display:none}
.bio-topic-performance{padding:88px 0 96px;background:var(--bio-navy);color:#fff}.bio-topic-performance h2,.bio-topic-performance h3{color:#fff}.bio-topic-performance-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:56px 40px}.bio-topic-performance-grid article h3{margin:0 0 18px;font-size:20px}.bio-topic-figure{height:320px;padding:18px;display:flex;align-items:center;justify-content:center;overflow:hidden;border-radius:8px;background:#fff;box-shadow:0 18px 36px rgba(0,0,0,.18)}.bio-topic-figure img{width:100%;height:284px;object-fit:contain}.bio-topic-performance-grid article p{margin:16px 0 0;color:#d4e2e8;font-size:14px;line-height:1.55}.bio-topic-performance-grid article p+p{margin-top:6px}.bio-topic-performance-grid article p strong{color:#82d2d0}.bio-topic-evidence-links{display:flex;gap:24px;margin-top:40px}.bio-topic-evidence-links a{color:#82d2d0;font-size:14px;font-weight:700}.bio-topic-evidence-links a:hover{color:#fff}
.bio-topic-related{padding:80px 0 88px;background:var(--bio-light)}.bio-topic-related-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:24px}.bio-topic-related-grid>a{overflow:hidden;border-radius:8px;background:#fff;box-shadow:0 10px 28px rgba(9,39,66,.08)}.bio-topic-related-grid img{width:100%;height:224px;object-fit:cover}.bio-topic-related-grid span{padding:22px 24px 24px;display:block}.bio-topic-related-grid strong{display:block;color:var(--bio-navy);font-size:18px}.bio-topic-related-grid b{display:block;margin-top:12px;color:var(--bio-teal-dark);font-size:15px}.bio-topic-related-grid>a:hover strong{color:var(--bio-teal-dark)}.bio-topic-related-grid>a:focus-visible{outline:3px solid var(--bio-teal);outline-offset:3px}
.bio-topic-contact{padding:28px 0 38px;background:#fff}.bio-topic-contact h2{margin-bottom:24px}.bio-topic-contact-grid{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:30px}.bio-topic-contact-item{min-height:48px;display:grid;grid-template-columns:44px minmax(0,1fr);gap:13px;align-items:center;color:var(--bio-text)}.bio-topic-contact-icon{width:42px;height:42px;display:grid;place-items:center;border:2px solid var(--bio-teal);border-radius:50%;color:var(--bio-teal-dark)}.bio-topic-contact-icon svg{width:18px;height:18px}.bio-topic-contact-item>span:last-child{font-size:14px;line-height:1.5}.bio-topic-contact-item strong{display:block;color:var(--bio-navy);font-size:13px}.bio-topic-contact-item:hover strong{color:var(--bio-teal-dark)}.bio-topic-contact-item:focus-visible{outline:3px solid var(--bio-teal);outline-offset:3px}
@media(max-width:960px){.bio-topic-assay-layout{grid-template-columns:1fr}.bio-topic-labeling{padding:28px 0 0;border-top:1px solid var(--bio-line);border-left:0}.bio-topic-labeling-methods{display:grid;grid-template-columns:1fr 1fr;gap:32px}.bio-topic-labeling-method+.bio-topic-labeling-method{padding-top:0}.bio-topic-labeling-method--amine .bio-topic-method-dot{top:2px}.bio-topic-filters{grid-template-columns:1fr 1fr}.bio-topic-search{grid-column:1/-1}.bio-topic-contact-grid{grid-template-columns:1fr 1fr;gap:24px 32px}}
@media(max-width:820px){.bio-topic-hero{height:300px}.bio-topic-hero-copy{max-width:65%}.bio-topic-hero h1{font-size:38px}.bio-topic-hero p{font-size:16px;line-height:1.5}.bio-topic-nav{top:0}.admin-bar .bio-topic-nav{top:46px}.bio-topic-nav .container{gap:28px}.bio-topic-nav .bio-topic-quick{display:none}}
@media(max-width:620px){.bio-topic-page h2{font-size:30px}.bio-topic-hero-media{object-position:62% center}.bio-topic-hero-copy{max-width:82%}.bio-topic-hero p{margin-bottom:20px}.bio-topic-overview,.bio-topic-assay,.bio-topic-products,.bio-topic-performance,.bio-topic-related{padding:56px 0}.bio-topic-highlights{grid-template-columns:1fr;gap:32px;margin-top:36px}.bio-topic-route-copy{grid-template-columns:1fr;gap:32px}.bio-topic-route-copy p{min-height:0}.bio-topic-route-copy strong{min-width:0}.bio-topic-labeling-methods{grid-template-columns:1fr;gap:16px}.bio-topic-groups,.bio-topic-filters{grid-template-columns:1fr}.bio-topic-search{grid-column:auto}.bio-topic-count{justify-content:flex-start;padding:0 16px}.bio-topic-product{grid-template-columns:1fr}.bio-topic-product-copy{padding:22px 20px}.bio-topic-product dl{display:grid;gap:5px}.bio-topic-product-data{min-height:180px;border-top:1px solid var(--bio-line);border-left:0}.bio-topic-product-data img{height:148px}.bio-topic-performance-grid,.bio-topic-related-grid,.bio-topic-contact-grid{grid-template-columns:1fr}.bio-topic-performance-grid{gap:48px}.bio-topic-figure{height:260px;padding:14px}.bio-topic-figure img{height:232px}.bio-topic-evidence-links{align-items:flex-start;flex-direction:column;gap:10px;margin-top:32px}.bio-topic-related-grid img{height:220px}.bio-topic-contact{padding:24px 0 32px}.bio-topic-contact-grid{gap:20px}.bio-topic-contact-item{min-height:56px}}
@media(min-width:821px) and (max-width:960px){body.page-template-page-biotinylated-proteins .header .nav-actions .button{display:none}}